Roguelike, The Legend of Zelda, a dual stick shooter, and the twisted mind of Edmund McMillen, part of the team behind Super Meat Boy. Put them all together and you've got The Binding of Isaac, a game that is as unhinged as it is entertaining, as good-looking as it is, well, disgusting. Even still, it's the kind of game you'll play through again and again, just to collect every item and explore every corner of the game's randomly-generated world.
Not quite a pipe puzzle and not quite a gear puzzle, Grayscale is a melding of the two genres into something both unique to play and easy on the eyes. The difficulty ramps up quite nicely and is enough to hold interest through the levels as you struggle to produce the black and white fireworks that denote success. Quite a lot of brain twisting, turning, and teasing bundled up into a beautiful little bow.