Hakim El Hattab's avoidance game Sinuous is as simple as it is lovely and easy to play. Use your mouse to guide your serpentine cursor safely through the field of red dots, snagging power ups to get various boosts and increase that all-powerful high-score. The longer you play, the more green dots will appear on your trail, which will let you sustain more direct hits.
While there isn't a whole lot of depth to be had to it, if you're going to play a game that demands twitchy reflexes you might as well spend time with one that also rewards you with some of the most soothing ambient music around and wraps it all up in one minimalistic, aesthetically pleasing package. It isn't something you'll likely play for long stretches of time, but it is an exceptionally nice and mellow example of the genre. After all, couldn't we all use a little more ommmmmmmmm in our day?
Note: You will need an HTML5-compatible browser to play this game.