Use the [WASD] or [arrow] keys to control your elephantine avatar through a number of quick mini-games, some of which hearken back to earlier elephant games. You may receive the instruction to save your girl, to climb some stairs, or even to kill yourself.
But not so fast. Sometimes the game will flash the text "DISOBEY" at you just after a level begins. When it does that, you've gotta do the opposite of what you'd normally do. Reject your girl, eschew the stairs, and cling to your will to live, for example.
Once you get the hang of that, you can unlock four more modes, including a blind mode where the screen goes dark just after starting, and a reverse mode where you must obey when it says disobey. Human sacrifice, elephants and spikes living together, mass hysteria!
Analysis: Obey the Game has the same kind of clinky arcade sounds and high energy techno soundtrack as its predecessors, which perfectly suits the flat, prismatic graphics. It's a world that, frankly, feels fun to mess around in.
A design flaw in the game, however, is that it doesn't really need you to mess around in it. I started a game and played to level 40, then let the game continue by itself. The game went all the way to level 253 before the elephant ran out of lives.
As the game keeps speeding up, in fact, fewer and fewer minigames become winnable if the wrong category of obey or disobey is ordered. The fan level, for example—by I think about level 90, it is literally impossible not to get sucked into the fan. Even if you are holding down on the right arrow key as the level comes up, you will still get sucked into the fan. So if that level comes up on "OBEY", you cannot win, and if it comes up on "DISOBEY", you cannot lose.
Another downside is the lack of mute and pause once you are in a game. There is a pause of a kind in the "coffee break" levels, where the music switches to a soothing elevator music, and you can't lose—except in reverse mode, where it's an automatic loss.
Microgame collections like this one tend to encourage the player to mash buttons, any buttons, so Obey the Game really innovates in the way that it requires the player to take a moment and wait for further instructions. The temptation to hit keys the moment the game changes is often the player's worst enemy.
Update: jmtb02 has updated the game to add mute and pause, and also changed it to a life gain every 3 levels passed in a row instead of every level passed. This does mitigate the problem of the game playing itself, but it doesn't change the fact that at higher levels a lot of the games are either unwinnable or unloseable depending on the luck of "obey" or "disobey". However, luck is a significant factor in the minigame genre anyway.
Don't play Obey the Game. DISOBEY!